COMPETITIVE ANTAGONISTS OF THYROXINE AND STRUCTURALLY RELATED COMPOUNDS* BY EARL FRIEDENt

نویسنده

  • RICHARD J. WINZLER
چکیده

Woolley (1) has prepared a number of ethers of N-acetyl-3,5-diiodotyrosine and found them to interfere with various effects of thyroxine on amphibian larvae. Some of Woolley’s observations were confirmed and extended by Winder and Frieden (2) and by Williams et al. (3). It is the purpose of this report to investigate the competitive nature of several thyroxine inhibitors and to determine the structural requirements for and the specificity of the inhibition of thyroxine and its active analogues,

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THE THYROXINE-LIKE ACTIVITY OF COMPOUNDS STRUCTURALLY RELATED TO THYROXINE* BY EARL FRIEDENt

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تاریخ انتشار 2000